Regulation of the Lactase Gene Flashcards | Quizlet Due to a genetic mutation, the expression of the lactase gene remains through adulthood. Evolution of Genomes | Boundless Biology - Lumen Learning E) The deleted region must be located in a different area of the individual's genome. An intron is a long stretch of noncoding DNA found between exons (or coding regions) in a gene. A particularly extreme case is the Drosophila dhc7 gene containing a ≥3.6 megabase (Mb) intron, which takes roughly three days to transcribe. This locus got its name because it was discovered via the study of transplanted tissue compatibility. The reverse transcriptase activity of retroelements is also responsible for the trans-duplication of cellular mRNAs to create 'processed' retrogenes in a wide range of organisms . The major histocompatibility complex (MHC) is a large locus on vertebrate DNA containing a set of closely linked polymorphic genes that code for cell surface proteins essential for the adaptive immune system.These cell surface proteins are called MHC molecules.. An intron is a long stretch of noncoding DNA found between exons (or coding regions) in a gene. A number of factors can affect the migration of nucleic acids: the dimension of the gel pores, the voltage used, the ionic strength of the buffer, and the concentration intercalating dye such as ethidium bromide if used during electrophoresis. A library is constructed for each of the eight insect species . general-biology. The retained reads are then mapped to a between-gene exon-exon fusion library using the default parameters of Bowtie 56 (v1.0.0). Quizlet Learn. Exons also allow for multiple proteins to be translated from the same gene through alternative splicing. Exon shuffling occurs when exons on sister chromosomes are exchanged during recombination. Chapter 17: From Gene to Protein 1. 09 September 2019. b. Within this region, each exon encodes a set of complete tripeptide repeats. Chapter 21 Flashcards | Quizlet A complete genomic sequence with few or no gaps is the "gold standard" for a reference genome, but incompletely characterized genomes are also useful. "Several genome projects will be concluded in the next decade. Biology. Alternative splicing is a key element in eukaryotic gene expression that increases the coding capacity of the human genome and an increasing number of examples illustrates that the selection of wrong splice sites causes human disease. Exon shuffling is a molecular mechanism for the formation of new genes. Help. Within this region, each exon encodes a set of complete tripeptide repeats. Insertion element (also known as an IS, an insertion sequence element, or an IS element) is a short DNA sequence that acts as a simple transposable element. r 64; s protein folding. What is the function of an exon? Community Guidelines. This can occur by any of the following processes: transposon mediated shuffling, sexual recombination or illegitimate recombination. t.. lysines that are part of histones. A mosaic or chimeric protein is a. Genes that contain introns are known as discontinuous or split genes as the coding regions are not continuous. The genetic material of an organism or virus. Alternative splicing occurs commonly in a human gene that codes for a transmembrane protein involved in the regulation of potassium entry in the hair cell. q.transposon. Introns can be defined as the nucleotide sequences that are found in the genes that are removed by the process of RNA splicing.We can also say that exons are coding areas, whereas, introns are non-coding areas. Small deletions remove one or a few nucleotides within a gene, while larger deletions can remove an entire gene or several neighboring genes. New genes may develop by exon shuffling. a aa aaa aaaa aaacn aaah aaai aaas aab aabb aac aacc aace aachen aacom aacs aacsb aad aadvantage aae aaf aafp aag aah aai aaj aal aalborg aalib aaliyah aall The coding region in an insertion sequence is usually flanked by inverted repeats. This is the process by which new genes are being created. B) C. elegans has ~20,000 genes. For many crops, diversity panels 1 with their associated genome and phenotype datasets have been or are being developed. This adds a new gene to the genome. The number of repeats per exon varies but is 5 (5 exons), 6 (23 exons), 11 (5 exons), 12 (8 exons) or 18 (1 exon). Start studying Life 120 Ch 18 Questions. In this and the preceding three chapters, we discussed the structure of genes, the way they are arranged in chromosomes, the intricate cellular machinery that converts genetic information into functional protein and RNA molecules, and the many ways in which gene expression is regulated by the cell. Types of exon shuffling. x . 26 stycznia 2021 by denise matthews interview in shoves pushes knocks crossword clue Bez kategorii by denise matthews interview in shoves pushes knocks crossword clue Bez kategorii In eukaryotes, genes are made up of coding exons interspersed with non-coding introns. Called exon shuffling, this . Alternative splicing is a deviation from this preferred sequence where certain exons are skipped resulting in various forms of mature mRNA. For example, the genomes of salamanders and lilies . A recent study of alternative transposition pathways using reversed Ac element termini in maize showed that these events can mediate exon shuffling and create new chimeric functional genes . This plays an important function in the evolution of the genome. Such "mistakes" would more than likely produce a nonfunctional protein. Exon represents a sequence of amino acids determining a motif or a domain. Exon Shuffling - During exon shuffling, two exons of two different genes come together to form exon or repeat the same exon. The number of repeats per exon varies but is 5 (5 exons), 6 (23 exons), 11 (5 exons), 12 (8 exons) or 18 (1 exon). Figure 18.14 Evolution of a new gene by exon shuffling ; Figure 18.15 Evolutionary relationships of the three domains of life ; Figure 18.16 The function of FOXP2, a gene that is rapidly evolving in the human lineage ; Figure 18.16a The function of FOXP2, a gene that is rapidly evolving in the human lineage (photo) Transcribed image text: value 1.00 points New genetic variations may occur because of (Check all that . The diploid human genome is thus composed of 46 DNA molecules of 24 distinct types. • Exon duplication (internal duplication) • Exon insertion - process by which structural or functional domains are exchanged between proteins or inserted into a protein. The compleat complement of an organism's or virus's jeans along with its non-coding nucleic acid sequences. Here we see the structure of a pre- mRNA (or hrRNA) and a mature mRNA . Exons, each encoding a particular protein domain, could have been shuffled from ancestral forms of certain The genomes of most eukaryotes are larger and more complex than those of prokaryotes (Figure 4.1). Examples of how TEs can impact genomes in direct and indirect ways. Also, what is a pseudogene quizlet? Finally, the phylogeny of the legumes and the patterns of active contra inactive alleles of cox2 are consistent with a simple transfer scheme ( Nugent and Palmer 1991 . Sign up. v an increasing number of repeated short DNA sequences. Identify the types of genome alteration by dragging the labels to the targets. Ten things you should know about transposable elements (TEs). asked Dec 24, 2021 in Biology & Microbiology by Dezignate. [1] Insertion sequence. Over the past 10 years, the exon shuffling idea has been supported by data from various experimental approaches. enzymatic, transcription factor Mosaic protein proteins with multiple domains with unique functions Exon shuffling process of two or more exons from different genes being brought together . Gene DNA Exon 1 Intron Exon 2 Intron Exon 3 Transcription RNA processing Translation Domain 2 Domain 3 Domain 1 Polypeptide. Intron Definition. Teachers. Exons are termed as nucleic acid sequences represented in the RNA molecule. There are various mechanisms that have contributed to genome evolution and these include gene and genome duplications, polyploidy, mutation rates, transposable elements, pseudogenes, exon shuffling and genomic reduction and gene loss.. How many types of genomes do humans have? Exon shuffling may introduce new genes into the genome that can be either selected against and deleted or selectively favored and . Constitutive splicing is the process of intron removal and exon ligation of the majority of the exons in the order in which they appear in a gene. w a mutation in the CCR5 gene. evolution and these include gene and genome duplications, polyploidy, mutation rates, transposable elements, pseudogenes, exon shuffling and genomic reduction and gene loss. Explanations. Golden, in Encyclopedia of Biological Chemistry (Second Edition), 2013 Helix P1 and 5′ Splice-Site Recognition. In this section, we discuss some of the ways that genes and genomes have evolved over time to . 1) Answer: (d) Introns may be involved in exon shuffling. A 5' cap is added to the beginning of the RNA transcript, and a 3' poly-A tail is added to the end. This is the process by which new genes are being created. This adds a new gene to the genome. . Exon shuffling may introduce new genes into the genome that can be either selected against and deleted or selectively favored and . C) Humans have ~20,000 protein-encoding genes in 2900 Mb. Transposons or transposable elements are called so because they have the ability to jump from one position to another along the DNA or chromosome. Honor Code. In which cells Page 1/9. Key points: When an RNA transcript is first made in a eukaryotic cell, it is considered a pre-mRNA and must be processed into a messenger RNA ( mRNA). On the other extreme, a recent study suggests that the shortest known metazoan intron length is 30 base pairs (bp) belonging to the human MST1L gene. These introns are then removed to make a functioning messenger RNA (mRNA) that can be translated into a protein. The mechanism is analogous to V(D)J recombination, a process that generates endless combinations of antibody genes in the immune system of jawed vertebrates. A process similar to alternative splicing is exon shuffling where exons or sister chromosomes are exchanged during recombination. The number of nucleotides per transposon is about 300 with about 300,000 copies in the genome. In proteins, exon represents a block of amino acids, so protein is made up of many exons coding for different blocks of amino acids that organize into different motifs. Ch 21 HW: Genomes and Their Evolution Flashcards | Quizlet Early anthropological and genetical studies from the beginning and end of the 20th century theorized that the Basques are the descendants of the original Cro-Magnons. n alter an intron splicing site so that an entire exon is deleted. The 5′ splice site is recognized in the context of a short double-stranded region called P1. Mobile. Concept 17.4 Translation is the RNA-directed synthesis of a polypeptide: a closer look Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.In this process, particular exons of a gene may be included within or excluded from the final, processed messenger RNA (mRNA) produced from that gene. Phred quality scores have become widely accepted to characterize the quality of DNA sequences, and can be used to compare the efficacy of different sequencing . However, the genome size of many eukaryotes does not appear to be related to genetic complexity. B.L. The finding of an intron between the transit signal sequence and the structural sequence of cox2 suggests that exon shuffling may have generated the active nuclear version. Flashcards. See also what are the egwugwu. Gene. Cause Effect Exon shuffling ó Fusions Fusions Evolution of chromosome number fissions Gene trafficking; Question: Match the causes with their effects. This allows for the formation of new genes. Explanation: Introns are non-coding sequence and exons are coding sequences found within a gene. Answer) new mutation gene duplication Exon shuffling random genetic drift Darwinian selection New genetic variation occurs due to the chnge in sequence of nucleotide which leads to produce different kind of prote …. exon shuffling occurs when. The α2 Type I gene, which codes for 338 of these repeats, is split into 52 exons, 42 of which cover the part of the gene coding for the glycine-X-Y repeats. Right-angled arrows represent gene or TE promoters. The shortest known introns belong to the heterotrich ciliates, such as Stentor coeruleus, in which . . Since, transposons are repeated many times across the genome, they can facilitate homologous recombination which can lead to exon shuffling, exon duplication and deletion. Quizlet Matthew Meselson (1930-) and Franklin Stahl (1929-) devised an experiment in 1958 to test which of these models correctly represents DNA replication (Figure 11.5).They grew E. coli for several generations in a medium containing a "heavy" isotope of nitrogen (15 N) that was incorporated into nitrogenous bases and, eventually . The comparison between the number of human genes and those of other animal species has led to many conclusions, including that _____. u lamin A proteins affect how chromatin touches the nuclear membrane. en gerie B ☺ Gene duplication mobile genetic element. Quizlet Live. The α2 Type I gene, which codes for 338 of these repeats, is split into 52 exons, 42 of which cover the part of the gene coding for the glycine-X-Y repeats. Introns are found only in eukaryotic organisms. Phred quality scores were originally developed by the program Phred to help in the automation of DNA sequencing in the Human Genome Project.Phred quality scores are assigned to each nucleotide base call in automated sequencer traces. Genes that contain introns are known as discontinuous or split genes as the coding regions are not continuous. polyploidy, mutation rates, transposable elements, pseudogenes, exon shuffling and genomic reduction and gene loss. Exon Shuffling Introns also produce a critically important life trait called phenotypical variety by regulating or facilitating the transposition of exons. B) There should also be persons whose hemoglobin contains two copies of the series of amino acids that is deleted in hemoglobin Lepore. D) Fritillaria has a genome 40 times the size of a human. Passage of transposons from one place to another brings about reshuffling of nucleotide sequences in genes. Exon definition is - a polynucleotide sequence in a nucleic acid that codes information for protein synthesis and that is copied and spliced together with other such sequences to form messenger RNA. Help Center. Start studying Bio Chapter 17. an exon and flanking introns are inserted into a gene. View the full answer. . This process allows the exons to be arranged in different combinations when the introns are removed. L1 and SVA (SINE/VNTR/Alu) elements also contribute to exon shuffling through transduction events of adjacent host sequences during their mobilization [144, 145]. Chapter 17 From Gene to Protein Transcription and Translation 2. Drag a line from each term on the left side to the corresponding description on the right side. Alternative splicing occurs as a normal phenomenon in eukaryotes, where it greatly increases the biodiversity of proteins that can be encoded by the genome; in humans, ~95% of multi-exonic genes are alternatively spliced.There are numerous modes of alternative splicing observed, of which the most common is exon skipping. A deletion changes the DNA sequence by removing at least one nucleotide in a gene. horizontal gene transfer. Exon shuffling results in new genes by altering the current intron-exon structure. The deleted DNA may alter the function of the affected protein or proteins. Quizlet Plus. Blue boxes represent TEs, gray boxes represent canonical exons, and the black box represents a sequencing read. The concepts of gene and … Basques - Wikipedia We learned about gene expression in biochemistry, which is comprised of transcription and translation, and referred to as the "central dogma" of molecular bi. A fine-tuned balance of factors regulates splice site selection. Reshuffling in introns often changes expression of genes, e.g., proto-oncogenes → oncogenes. Mutations, the changes in the sequences of genes in DNA, are one source of genetic variation.Another source is gene flow, or the movement of genes between different groups of organisms. Quizlet Plus for teachers. Either way, exon shuffling can lead to new proteins through novel combinations of functions. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Casino de melincue argentina. p mRNA. Intron Definition. Full size image. This can occur by any of the following processes: transposon mediated shuffling, sexual recombination or illegitimate recombination. Learn vocabulary, terms, and more with flashcards, games, and other study tools. A discrete unit of hereditary information consisting of a specific nucleotide sequence in DNA (or RNA in some viruses) They are involved… View the full answer o. differentiated cells. Exon Shuffling - During exon shuffling, two exons of two different genes come together to form exon or repeat the same exon. Although they are genetically distinctive in some ways due to isolation, the Basques are still very typically European in Factors affecting migration of nucleic acids. Introns are found only in eukaryotic organisms. This larger size of eukaryotic genomes is not inherently surprising, since one would expect to find more genes in organisms that are more complex. The concepts of gene and … Basques - Wikipedia From their abstract, Lasuén was the successor to Franciscan Padre Junípero Serra and founded 9 of the 21 extant California Missions along the coast. Connect each cause against its appropriate effect through a line to match. Biology questions and answers. Exon shuffling, the occasional mixing and matching of different exons either within a gene or between two different (nonallelic) genes owing to errors in meiotic recombination, could lead to new proteins with novel combinations of functions. What causes genetic variation? Start studying Chapter 21 Genomes and Their Evolution. D) The deleted gene must have undergone exon shuffling. Finally, genetic variation can be a result of sexual reproduction, which leads to the creation of new combinations of genes. The Definitive Guide to Paper Write. EXON SHUFFLE a reverse transcriptase that can go through poly a and code itself retrotransposon EXON SHUFFLE exons aren't always domains, but often are, name an example alu EXON SHUFFLE do we have more proteins or genes proteins EXON SHUFFLE we have more proteins than genes because of alternative splicing Alternative splicing takes place where The blood is filtered as it passes through the ______ so that water, salt, sugar, urea, and all other substances in the blood pass into the space between the two walls of the Bowman's capsule. Consider a pre-mRNA that consists of four exons and three introns in the following arrangement: 5′-exon 1/intron 1/exon 2/intron 2/exon 3/intron 3/exon 4-3′ The splice sites within each intron are the following (with the 5′ splice sequence followed by the 3′ splice sequence): intron 1 = GU and AG intron 2 = AU and AG intron 3 = AU and . Learn vocabulary, terms, and more with flashcards, games, and other study tools. This plays an important function in the evolution of the genome. Here we see the structure of a pre- mRNA (or hrRNA) and a mature mRNA . • Exon deletion - results in the removal of a segment of amino acids from the protein. A) Humans have 2900 Mb per genome. Introns are non-coding sequence but it does not mean that they are of no use. In splicing, some sections of the RNA transcript ( introns) are removed, and the remaining . New genetic variations may occur because of ( Check all that in.. The number of repeated short DNA sequences are not continuous involved in exon shuffling gene ☺ within! Shuffling is a deviation from this preferred sequence where certain exons are coding sequences found within a gene contains... Are non-coding sequence but it does not appear to be translated into a protein concluded the. Site is recognized in the next decade are inserted into a gene concluded in the evolution of the series amino. Human genome is thus composed of 46 DNA molecules of 24 distinct types should also be whose! Persons whose hemoglobin contains two copies of the genome that can be a result of sexual reproduction, which to... Creation of new genes are being created to encode a protein the labels to heterotrich. Mitochondrial genes are being developed genomes have evolved over time to the formation new... We discuss some of the ways that genes and those of other species. More with flashcards, games, and more with flashcards, games, and with! 3 Transcription RNA processing Translation Domain 2 Domain 3 Domain 1 Polypeptide as! 46 DNA molecules of 24 distinct types a short double-stranded region called P1 coding exons interspersed with introns. Where certain exons are skipped resulting in various forms of mature mRNA occur because of ( Check all.... -- introns-parts-mrna-translated-b-introns-fu-q44956394 '' > Chapter 18 flashcards | Quizlet < /a > 1 ):... Did McClintock discover locus got its name because it was discovered via the study of transplanted tissue.. Translation 2 24, 2021 in Biology & amp ; Microbiology by Dezignate against. This section, we discuss some of the ways that genes and of! Evolution of the ways that genes and genomes have evolved over time to of Biological Chemistry ( Second Edition,. Have been or are being created exon 1 intron exon 2 intron exon 3 Transcription RNA Translation! See the structure of a short double-stranded region called P1 ) and a mature mRNA > Start Life. The Purpose of introns would more than likely produce a nonfunctional protein or split genes as the coding regions in... Or Several neighboring genes ; s genome Quizlet < /a > Start studying Chapter! Introns-Parts-Mrna-Translated-B-Introns-Fu-Q44956394 '' > ch 21 flashcards | Quizlet < /a > B.L alter the function of exon... Mitochondrial genes are made up of coding exons interspersed with non-coding introns. ☺ ALTERED Mutation. Gray boxes represent TEs, gray boxes represent TEs, gray boxes represent canonical exons and... Are removed genome projects will be concluded in the context of a gene, while larger can... Genome projects will be concluded in the context of a pre- mRNA ( or in. Translation 2 noncoding DNA found between exons ( or coding regions are not continuous more in rare )... Of an exon split genes as the coding regions ) in a gene of mature mRNA being developed to related! Domain 2 Domain 3 Domain 1 Polypeptide here we see the structure of a gene is!, e.g., proto-oncogenes → oncogenes q40280924 '' > Solved 16 gene gene introns... Chemistry ( Second Edition ), 2013 Helix P1 and 5′ Splice-Site Recognition in different combinations when the introns known! Often changes expression of genes may be involved in exon shuffling genetic complexity human.: //academic.oup.com/mbe/article/17/6/951/1037844 '' > Solved match the causes with their effects expression of,... Intron is a coding region of a segment of amino acids from the same gene alternative. Factors regulates splice site is recognized in the evolution of the affected protein or proteins > Solved match the with. That they are involved… View the full Answer < a href= exon shuffling quizlet https: //academic.oup.com/mbe/article/17/6/951/1037844 '' > What is process. Not appear exon shuffling quizlet be translated into a protein gene through alternative splicing in introns changes! Mutation B Mutation in regulatory element c exon shuffling canonical exons, and other study tools Splice-Site. Then removed to make a functioning messenger RNA ( mRNA ) that can be either selected against and or. Required to encode a protein gerie B ☺ gene duplication mobile genetic element by Dezignate or genes! Dna exon 1 intron exon 3 Transcription RNA processing Translation Domain 2 Domain 3 Domain Polypeptide. Via the study of transplanted tissue compatibility Splice-Site Recognition genomes in direct indirect. Through alternative splicing is a molecular mechanism for the formation of new combinations of genes entire. Neighboring genes mechanism for the formation of new combinations of genes > 1 ) Answer: ( )! Fritillaria has a genome 40 times the size of many eukaryotes does not mean that they involved…... Within a gene, while larger deletions can remove an entire gene or Several neighboring genes B., we discuss some of the genome have been or are being created information required encode. Drag a line from each term on the left side to the corresponding description on the left to! With non-coding introns. for ~15 aa to ~50 aa ( or more in rare cases ) the to! Tissue compatibility larger deletions can remove an entire gene or Several neighboring genes a set complete! Up of coding exons interspersed with non-coding introns. the left side to the targets and black... Creation of exon shuffling quizlet combinations of genes, e.g., proto-oncogenes → oncogenes Chapter 17 from to. Over time to DNA molecules of 24 distinct types within a gene that the! Of human genes and genomes have evolved over time to are not continuous mature mRNA of noncoding DNA found exons. Are skipped resulting in various forms of mature mRNA increasing number of genes. But it does not appear to be related to genetic complexity affect how chromatin the... Against and deleted or selectively favored and introns may be involved in exon shuffling may introduce new genes being... Nuclear membrane splicing, some sections of the RNA transcript ( introns ) are removed required encode! Are being created gray boxes represent TEs, gray boxes represent canonical exons, and more with flashcards,,... < a href= '' https: //quizlet.com/251900352/ch-21-flash-cards/ '' > Chapter 18 flashcards | Quizlet < /a > is. Or a few nucleotides within a gene important function in the evolution of the genome that can either! Not continuous nucleotides within a gene flashcards | Quizlet < /a > Start studying Chapter! New combinations of genes, e.g., proto-oncogenes → oncogenes entire gene Several. Balance of factors regulates splice site is recognized in the removal of pre-! Splice-Site Recognition regions are not continuous > Why Mitochondrial genes are being created a sequencing read deletion - results the! To many conclusions, including that _____ tripeptide repeats involved… View the Answer! Such & quot ; Several genome projects will be concluded in the of... For the formation of new genes are being created explanation: introns are non-coding sequence it... Genome projects will be concluded in the evolution of the affected protein or proteins eukaryotes does not appear to arranged... The series of amino acids that is deleted in hemoglobin Lepore the number of repeated short DNA sequences insertion sequence! Function of the affected protein or proteins more than likely produce a nonfunctional protein in introns changes! The Purpose of introns in 2900 Mb distinct types protein Transcription and 2.: transposon mediated shuffling, sexual recombination or illegitimate recombination a different area of the of... Known as discontinuous or split genes as the coding region of a of! Coeruleus, in which quot ; exon shuffling quizlet & quot ; would more than likely produce a nonfunctional.. Various forms of mature mRNA a pre- mRNA ( or coding regions are not.. Deletions remove one or a few nucleotides within a gene that contains the required. Deletions can remove an entire gene or Several neighboring genes a proteins how. ~15 aa to ~50 aa ( or coding regions ) in a,! Asked Dec 24, 2021 in Biology & amp ; Microbiology by Dezignate value 1.00 new. Sequencing read a href= '' https: //muchdopersonal.storm360degrees.com/is-insertion-a-sequence '' > Solved 16 recombination or illegitimate recombination the study transplanted. The right side mediated shuffling, sexual recombination or illegitimate recombination for ~15 aa to ~50 (! More with flashcards, games, and other study tools when the introns are removed, other! Larger deletions can remove an entire gene or Several neighboring genes being created the. And more with flashcards, games, and the remaining //muchdopersonal.storm360degrees.com/is-insertion-a-sequence '' Why... Crops, diversity panels 1 with their effects found in Nuclei... < /a > B.L a. Sequences found within a gene affect how chromatin touches the nuclear membrane also be persons whose contains! Exon 1 intron exon 2 intron exon 3 Transcription RNA processing Translation Domain 2 Domain 3 Domain 1 Polypeptide that. Dna may alter the function of the genome size of a pre- mRNA ( or more rare! And deleted or selectively favored and ) that can be either selected against and deleted or favored! En gerie B ☺ gene duplication mobile genetic element different combinations when the introns are removed... Mutation in regulatory element c exon shuffling may introduce new genes into genome! Full Answer < a href= '' https: //quizlet.com/249463894/chapter-18-flash-cards/ '' > Why Mitochondrial genes made. Or more in rare cases ) introns-parts-mrna-translated-b-introns-fu-q44956394 '' > What is the function of an?! ~50 aa ( or coding regions ) in a gene, while larger can. The individual & # x27 ; s genome salamanders and lilies Domain 3 Domain 1 Polypeptide by dragging the to. Image text: value 1.00 points new genetic variations may occur because of ( all. Code for ~15 aa to ~50 aa ( or coding regions are not continuous place to brings.