tina huang data scientist tina huang data scientist

PLoS Biol. A series of f4-symmetry statistics confirm that all the Epigravettian-associated individuals are cladal, and do not share excess affinity with any local (Paglicci 12) or non-local preceding ancestries (Goyet Q116-1, Kostenki 14, Malta 1 or Vstonice) (Supplementary Data 2.F). PLoS Genet. Echinacea. 15-star ratings) or unstructured data (such as social media reviews). Admixture events were dated using the ancestry covariance pattern-based DATES 753 program105, with a bin size of 0.1 cM for covariance calculation and the start of exponential fitting at d0.5cM. The inferred topology reveals a phylogeographic pattern irrespective of individual ages. Quat. However, the research team found no evidence for this, on the contrary: hunter-gatherer populations associated with the Gravettian culture and living in central and southern Europe are no longer genetically detectable after the LGM. Greater San Diego Area. Front. (Robert Rueda; Tina Saldivar; Lynne Shapiro; Shane Templeton; Houghton Mifflin Company Staff) 2022-112-4f84b - Ecologizr. Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments. I am Tina Huang, PhD, a data scientist, and the director of the Data Science Learning Center at the University of Arizona. Modern humans have populated Europe for more than 45,000 years1,2. Between 14 and 8ka, all hunter-gatherers in western and central Europe carried only Oberkassel ancestry, with no detectable contribution from the Sidelkino cluster. These models are easy to implement as well as really helpful in deciding what to build and how much to invest in it. Commun. The genetic prehistory of the Baltic Sea region. A dynastic elite in monumental Neolithic society. Here is a sampling of five herbs that have demonstrated potential immune support benefits: 1. Natural Language Processing (NLP) is another technique that has a well-deserved position in product development. Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers. 4b and Supplementary Data 3.C). The IntCal20 Northern Hemisphere radiocarbon age calibration curve (055 cal kbp). This is . Planning and Learning in Partially Observable Systems via Filter Stability Noah Golowich (MIT); Ankur Moitra (Math & CSAIL, MIT); Dhruv Rohatgi (MIT) New Subset Selection Algorithms for Low Rank Approximation: Offline and Online David P. Woodruff, Taisuke Yasuda (Carnegie Mellon University) Good Quantum LDPC Codes with Linear Time Decoders Irit Dinur (Weizmann); Min-Hsiu Hsieh (Hon Hai Quantum . Interactions between people from central and eastern Europe can only be detected again from 8,000 years ago. She was not prepared for the complexity of a typical programming language. 8). 3.Tina Huang. 7,794 followers. The length of the colour bar shows the proportion of each ancestry. Furthermore, the findings show that there had been no genetic exchange between contemporaneous hunter-gatherer populations in western and eastern Europe for more than 6,000 years. F-statistics suggest that Le Piage II is genetically intermediate between Fournol 85 and El Mirn (Supplementary Data 2.D). I came across her YouTube through Ken Jee. Laplace, G. Essai de Typologie Systmatique (Annali dellUniversit di Ferrara, 1964). Science 366, 708714 (2019). Gamble, C., Davies, W., Pettitt, P., Hazelwood, L. & Richards, M. The archaeological and genetic foundations of the European population during the Late Glacial: implications for agricultural thinking. This affinity is even stronger towards Epigravettian-associated individuals from western and central Italy and Sicily (group 2 and group 3, respectively) than to those from northern Italy (group 1) (Supplementary Data 2.F). Its mainly used in industries such as finance, insurance, healthcare, and insurance-related apps such as credit card applications, vehicle purchasing, etc. Trzej niedwiedzi braciszkowie przeywaj swoje dziecistwo, pakujc si w najrozmaitsze tarapaty za spraw magicznego pudeka. Natl Acad. English company number 3898053New York | Boston | Chicago | Austin | Toronto | Brighton | London | Copenhagen | Berlin | Stuttgart | Frankfurt | Paris | Madrid | Budapest | Sofia | Chennai | Singapore | Sydney | Melbourne. The pre-40kagroup and theFournol and Vstonice clusters are marked as shaded areas in different colours. This may have prompted people from the south to expand their habitat. Learn with a sense of purpose. . 7 and Supplementary Table 3), which coincides roughly with the first appearance of the Oberkassel ancestry in central Europe. An early modern human from Romania with a recent Neanderthal ancestor. The 3 Greatest Moments in science library uga hours History, Addicted to hills science diet adult small bites? University Universit Chouaib Doukkali; . During this time agriculture and a sedentary lifestyle spread from Anatolia to Europe. Kotula, A., Piezonka, H. & Tergerger, T. The Mesolithic cemetery of Gro Fredenwalde (north-eastern Germany) and its cultural affiliations. Google Scholar. In sum, we describe the formation and interaction between the Oberkassel and Sidelkino clusters, the two main hunter-gatherer ancestries present in Europe from 14ka onwards. A phylogeographic reconstruction of different lineages carrying this ancestry further suggests its entry point into northeastern Italy from the Balkans followed by a north-to-south expansion into the Italian peninsula alongside a population decline through sequential bottlenecks. "Presumably, these people came from the Balkans, arrived first in northern Italy around the time of the glacial maximum and spread all the way south to Sicily.". The oldest individual in the Fournol cluster is Ormesson 2988 from northeastern France (31ka, Early/Middle Gravettian), whereasa Gravettian group from Goyet in Belgium (27ka, Late Gravettian) is found to be a mixture between the Vstonice and Fournol clusters. Meyer, M. & Kircher, M. Illumina sequencing library preparation for highly multiplexed target capture and sequencing. Its like the different ingredients in your recipe. The genomic history of the Iberian Peninsula over the past 8,000 years. Write a sharp and effective resume in minutes and get noticed by employers. It can take several minutes for a query to complete, and if youre using a lot of data the whole table may be locked up. Sci. In article number 2206752, Hao Zeng and co-workers report a soft actuator assembly capable of windassisted dispersal and lift-off/landing action under the control of a light beam.The design is inspired by the seed of dandelion, resembling several biomimetic features, i.e., high porosity, lightweight, and separated vortex ring generation under a steady wind flow. PubMed Metadata information of studied individuals. Tina teaches SQL in data science in addition to this basic material. Interviewed Taiwanese designers and analyzed the interview data. The Solutrean culture is temporally intermediate between the Gravettian and the Magdalenian (or the Badegoulian) cultures, and is found in southwestern and western Europe, which are considered to have been climatic refugia for human populations during the LGM25,26. Okenla is also part of Atomicos Angel Programme 2021, and is an advisory board member for both Coders of Colour and the No.10 Innovation Fellowship. In panel a, genetic affinity between different ancestries is indicated by thick lines or shades, while admixture is indicated with arrows. Evol. Its the complexity of product development, with all of its moving parts, that makes data immensely powerful. Here we analyse 356 ancient hunter-gatherer genomes, including new genomic data for 116 individuals from 14 countries in western and central Eurasia, spanning between 35,000 and 5,000 years ago. Notably, this genetic distinction coincides with dissimilarities in mortuary practice among genetically analysed Gravettian-associated individuals from different parts of Europe. Required fields are marked *. My name is Tina and I'm a data scientist and YouTuber. In this period, the Oberkassel-ancestry admixture spread further east, reaching Samara by around 6.5ka, and an increase in Sidelkino ancestry was detected in hunter-gatherers from the Baltic region, which was previously associated with the transition from the Narva culture to the Comb Ceramic culture38,39 (Extended Data Fig. It requires countless decisions to get them right, many of which have not been as straightforward at first. Modern humans have populated Europe for more than 45,000 years 1, 2. Biol. Charlton, S. et al. Are you Tina Huang? Svensson, E. et al. Highly Influential Citations 3. In no time, she established herself as one of the favorite vloggers of the data community. Correspondence to 4 Admixture graph modelling of pre-34 ka hunter-gatherer lineages. L. Sineo, M.L. The analysed genomes also show that the descendants of these Epigravettian inhabitants of the Italian peninsula spread across the rest of Europe about 14,000 years ago, replacing populations associated with the Magdalenian culture. Proc. And if youre new to data science, check out the 365 Intro to Data and Data Science course. She has been working for the data sciences industry since 2014. Protoc. The LGM could thus have created a corridor south of the Alps for east-to-west human movements that genetically connected hunter-gatherer populations from the Balkans to Iberia, possibly also via dispersals along existing lower-sea-level coasts32. This might also explain the genetic uniformity of the Oberkassel cluster across large parts of western Eurasia but genomic data from between 15 and 14ka is needed to understand the exact dynamics of this turnover. 9) and testing the relative affinity among them using f4-statistics in the form f4(Mbuti, Epigravettian A; Epigravettian B, Epigravettian C) (Supplementary Data 2.E). It is often considered as a pan-European cultural mosaic with regional variations in material to symbolic productions20,21. 31, 24842493.e7 (2021). Genomic data have shown that modern humans were present in western Eurasia1,2 at least 45ka. Fifth, the Oberkassel ancestry in western and central Europe and the Sidelkino ancestry in eastern Europe remained largely isolated for almost 6,000 years until genetic interactions were first observedaround 8ka in northeastern Germany, possibly associated with cultural exchanges along the Baltics49 and around 7.5ka in the upper Volga region, possibly linked to the spread of pottery in the region50. Evol. The 10 mock interviews provide a great detailed approach to solving any SQL questions. Oxidation of methane into valuable chemicals, such as C 2+ molecules, has been long sought after but the dilemma between high yield and high selectivity of desired products remains. ), no. 2023 365 Data Science. Mid and Late Upper Palaeolithic in the Adriatic Basin: chronology, transitions and human adaptations to a changing landscape. The PCA was carried out by smartpca in EIGENSOFT 6.0.1102, with modern individuals used for calculation and all the ancient individuals projected on the calculated PCs. The formation of human populations in South and Central Asia. I have an undergraduate degree in . Here, we report genomic data from 4 individuals, including 3 approximately 13,000-year-old genomes from northeastern Italy (Pradis 1), northwestern Italy (Arene Candide 16) and Sicily (San Teodoro 2), as well as increased genome-wide coverage from Tagliente 215 dated to 17ka. This course will help you build a deliberate strategy when participating in a data scientist job interview involving SQL. Notably, the Fournol ancestry provides a better proxy than Goyet Q116-1 for the genetic component found in the GoyetQ2 cluster and in El Mirn (Supplementary Data 2.H). Last Name Huang #8. 1c and Extended Data Fig. and T. Saupe received support from the European Union through the European Regional Development Fund (project no. Bioinformatics 25, 17541760 (2009). Present-day individuals (gray dots) genotyped on theHumanOrigins dataset are used to define the PCA variation onto which ancient genomes (coloured symbols) are projected. For phylogenetic reconstruction (Extended Data Fig. Check out The data science resume that got me my FAANG job and subscribe to Tina Huangs YouTube channel. Develped strategies for promoting G-Mark to Taiwan. We then removed samples with less than 0.04X coverage (calculated on the mappable, non-recombining region of the Y chromosome98) to avoid arbitrarily placing low-coverage samples at the root of major haplogroups. 1 and 2). We love meeting interesting people and making new friends. 32, 17921797 (2004). PubMed Central The deduplicated bam files were filtered using PMDtools 0.6068 with a threshold of 3, to reduce potential modern DNA contamination based on postmortem DNA deamination. Contrary to West Siberian hunter-gatherers, Tutkaul 1 does not carry an extra eastern Eurasian ancestry, but shows affinity to Iranian Neolithic farmers and some younger populations from Iran and the Turan region (Supplementary Data 2.L). It is not intended to provide medical or other professional advice. Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry. USA 110, 22232227 (2013). Olalde, I. et al. Archaeological background, method descriptions and discussions additional to the main text, including sections 113, Figs. . EAGER: efficient ancient genome reconstruction. Unlike setting up a Premium subscription to our platform, for which you would be billed monthly or annually, acquiring individual courses requires a one-time payment only. Conversely, individuals in the Sidelkino cluster are genetically closer to AG3 than Tutkaul 1. Tina started her YouTube channel in 2020. Reviews. Individuals and groups are plotted with the same colours and symbols as in Fig. Fu, Q. et al. Check out my courses where we apply scientifically backed learning techniques to accomplish our goals. In other words, youll never have to worry about validity issues or having to re-take the course after a certain amount of time. The lsqproject: YES parameter was used to minimize the effect of missing data in ancient individuals. The code for the newly developed ROH based contamination estimate method is available at https://github.com/hyl317/hapROH. Rohland, N. & Hofreiter, M. Ancient DNA extraction from bones and teeth. R. Soc. Then the cleaned reads together with cleaned reads from 1240k capture sequencing were mapped to human reference mitochondrial sequence NC_012920.1 with BWA 0.7.12 aln/samse algorithm (parameters n 0.01, l 16500) and realigned with CircularMapper64. The sample size of individualpairsincluded in each groupis reported in SupplementaryData 3.A. The mtDNA contamination was estimated by Schmutzi (--notusepredC --uselength)69 for all the libraries. Villalba-Mouco, V. et al. Our results show that the contact zone and the admixture patterns betweenthe Oberkassel and Sidelkino ancestries changed over time (Fig. Grizz, Panda i Lodomir maj rne charaktery, ale pomimo odmiennoci potrafi wspdziaa i wspiera si w kopotach. In this debated framework, Gravettian-associated individuals have been suggested to represent a biologically homogeneous population on the basis of craniometric and genomic data4,22. Science 360, eaar7711 (2018). Preistoria e Antropologia, Universit degli Studi di Siena, Siena, Italy, Stefano Ricci,Francesco Boschin&Annamaria Ronchitelli, Centro Studi sul Quaternario ODV, Sansepolcro, Italy, Institut National de Recherches Archologiques, Bertrange, Luxembourg, Department of Cultural Heritage, University of Bologna, Ravenna, Italy, Gregorio Oxilia,Eugenio Bortolini,Stefano Benazzi&Matteo Romandini, Human Ecology and Archaeology (HUMANE), Department of Archaeology and Anthropology, Instituci Mil i Fontanals de Investigacin en Humanidades, Consejo Superior de Investigaciones Cientficas (IMF - CSIC), Barcelona, Spain, UMR 7209Archozoologie et Archobotanique-Socits, Pratiques et Environnements, Musum National dHistoire Naturelle, Paris, France, Dipartimento di Scienze Della Vita e DellAmbiente, Sezione di Neuroscienze e Antropologia, Universit Degli Studi di Cagliari, Cittadella Monserrato, Cagliari, Italy, Dipartimento di Civilt e Forme Del Sapere, Universit di Pisa, Pisa, Italy, Center for Isotope Research, Groningen University, Groningen, The Netherlands, UMR 7206 co-Anthropologie, quipe ABBA. Otte, M.) 105160 (Errance, 2013). Sci. By using our site you agree toour 9 posts. Both newly sequenced genomes from Solutrean-associated individuals (Le Piage II (23ka) from southwestern France and La Riera (level 14, 21ka) from northern Spain) show a generalized affinity with members of the Fournol and GoyetQ2 clusters in outgroup f3-statistics (Supplementary Data 2.A). Data warehousing is a field where you often have to deal with a lot of raw data. On the basis of f4-statistics, we find that individuals assigned to the Oberkassel cluster are closer to the Arene Candide 16 genome than any other Epigravettian-associated group from Italy (Supplementary Data 2.F). Finally, unsupervised clustering and more complex techniques, such as deep learning, also have their place. Were dedicated to providing you the best ofNews, with a focus on dependability andBusiness. Ontario Institute for Cancer Research Toronto, ON. Cuando se ampla, se proporciona una lista de opciones de bsqueda para que los resultados coincidan con la seleccin actual. Cold Spring Harb. PubMed We report 47 new radiocarbon dates performed on skeletal elements of 40 individuals by the Curt-Engelhorn-Zentrum Archaeometrie in Mannheim (MAMS, n=29), Center for Isotope Research, University of Groningen (GrA and GrM, n=5), University of Aarhus (AAR, n=3), Beta Analytics (Beta, n=2), Zrich (ETH, n=3), International Chemical Analysis (ICA, n=2), Natural History Museum in Paris (Echo Lab, n=1) and Vilnius (FTMC, n=2) (Supplementary Data 1.A). Antiquity 91, 573588 (2017). Srie Prhistoire dEurope 9 (ditions, 2001). 12). 4. Then we combined our newly generated genotypes with published genotypes from ancient and modern individuals from AADR v42.4 (Allen Ancient DNA Resource (https://reich.hms.harvard.edu/allen-ancient-dna-resource-aadr-downloadable-genotypes-present-day-and-ancient-dna-data) version 42.4) for downstream analysis1,4,7,14,16,23,36,37,38,39,40,42,43,45,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94. Moreover, we reveal a north-to-south decrease in genetic diversity among the Epigravettian-associated groups, with the highest PMR and heterozygosity values found in northern Italian individuals (group 1), intermediate in western and central Italian individuals (group 2) and the lowest in Sicilian individuals (group 3) (Fig. 5, 820825 (2021). Sign In Create Free Account. Bortolini, E. et al. Korlevi, P. et al. Lifetime access to all course materials and updates. Quat. Proc. The latter was created as a support network for women in the industry to discuss, share, and learn from each other.. a, MDS plot of pre-LGM individuals. Overall, the literature suggests that Chinese Canadian students demonstrate high levels of achievement and that this academic success is associated with factors such as stronger feelings of ethnic identity, better English language skills in the family, Chinese . c, Admixture graph modelling of the main pre-LGM European hunter-gatherer lineages created using qpGraph. 4, 11 (2007). Tina K. Sorensen. Tina Huang I'm a data scientist, youtuber, and the first Lonely Octopus . We use cookies to improve your experience and give you personalized content. S. Shnaider received support from theRussian Science Foundation (no. Both of these books focus on the science and math behind data mining. 803147-RESOLUTION (to S.T. Ecol. received support from the Estonian Research Council grant PUT (PRG243). assembled archaeological material, descriptions and interpretations. Rivollat, M. et al. Previous studies have shown that two main hunter-gatherer ancestries were predominant across most parts of Europe after around 14kathat is, the western hunter-gatherer (WHG) ancestry, related to the Villabruna cluster, and the eastern hunter-gatherer (EHG) ancestry, showing affinity to both the Villabruna and the ancient north Eurasian (ANE) ancestry found in Upper Palaeolithic Siberian individuals4,36. Join a growing community of 11K+ to find accountability partners, take part in productivity sprints, and join discord only events! USA 111, 22292234 (2014). After the LGM, a genetic component distantly linked to the Goyet Q116-1 individual from Belgiumdated to 35 kanamed GoyetQ2 ancestry(hereafter, GoyetQ2 cluster or ancestry)reappeared in individuals from southwestern and central Europe associated with the Magdalenian culture (1914ka from Iberia to eastern Europe across central Europe) and in an admixed form in subsequent Final Palaeolithic and Mesolithic hunter-gatherers4,14, but the geographic extension of this ancestry is still unclear. Claim Author Page. Feldman, M. et al. First Name Tina. This is in sharp contrast to the genetic history of Iberian hunter-gatherers, where the spread of the Villabruna/Oberkassel ancestry involved multiple local admixture events with groups carrying high proportions of GoyetQ2 ancestry14 (Fig. The previously described Vstonice cluster, including a newly reported 29,000-year-old individual from Paglicci cave (Paglicci 12) in southern Italy, is closely related to the previously published genomes from Sunghir and Kostenki 12 in western Russia, which are dated to 34ka and 32ka, respectively4,23. Adv. As long asyouget a exam score of 60% or above,youare eligible toreceive aCourse Certificate! Genetic sexing revealed 78 maleindividuals and 38 femaleindividuals (Supplementary Fig. Tina Huang Popularity . Science 346, 11131118 (2014). 2022 Weird Science Plus - All Rights Reserved. Hi! Article We built 1 to 8 single- and double-stranded genetic libraries for each individual and enriched them for human DNA on 1.24million single nucleotide polymorphisms6 (SNPs), which were then sequenced and yielded 0.04- to 7.64-fold coverage on average over the targeted SNPs. Additional details are provided in SupplementaryInformation, section11 and SupplementaryTable 3. Big data data warehousing and data science are two sub-tasks of a larger endeavor called data science, which is a sub-tasks of data science. Citations 52. wrote the manuscript with input from T.T., E.A., W.H., J. Krause and all other co-authors. Peresani, M. et al. Schmitt, T. Molecular biogeography of Europe: Pleistocene cycles and postglacial trends. You'll likely won't meet her on a day to day basis, but she's always lurking in the Discord and following everybody's progress (not . . 3b). Rohrlach, A. http://creativecommons.org/licenses/by/4.0/, Ancient genomes show how humans escaped Europes deep freeze. Parallel palaeogenomic transects reveal complex genetic history of early European farmers. Skoglund, P. et al. Lazaridis, I. et al. Resurrected Supernova Provides Missing-Link, Bald Eagles Aren't Fledging as Many Chicks, Ultracool Dwarf Binary Stars Break Records, Deflecting Asteroids to Protect Planet Earth, Quantum Chemistry: Molecules Caught Tunneling, Shark from Jurassic Period Highly Evolved, 2.9-Million-Year-Old Butchery Site Reopens Case of Who Made First Stone Tools, Gut Microbes Can Boost the Motivation to Exercise, Warmer Climate May Drive Fungi to Be More Dangerous to Our Health, Seawater Split to Produce 'Green' Hydrogen. 9 Graphical summary depicting the main genetic transformations in post-40 ka hunter-gatherers from Europe. Fu, Q. et al. Evol. No, there are no prerequisites for enrolling. Note added in proof:A companion paper51describes genome-wide data of a 23,000-year-old Solutrean-associated individual from southern Iberia that extend the evidence of genetic continuity across the LGM in southwestern Europe. The grouping of Epigravettian-associated populations is shown with the same colour in a. Edit your profile. Originally published at https://365datascience.com on October 1, 2020. a, Geographic locations of newly reported individuals (filled symbols with black outline) and representative previously published individuals (outlined stars). Taipei, Taiwan . Youll be surprised how much value there is in a quick XGBoost model, for example. YourCourse Certificatehas no expiration date. Data warehousing is a relatively new field that focuses on the use of large datasets for analytical purposes. c, MDS plot of European hunter-gatherers based on 1f3(Mbuti; pop1, pop2). Genome Biol. Tina started her YouTube channel in 2020. The phylogenetic reconstruction of Epigravettian-associated genomes, with Pradis 1 diverging more deeply than all others, indicates that the turnover took place much earlier than 17kathe date of the more derived Tagliente 2 genome. is supported by a Ramn y Cajal fellowship (RYC-2017-22558). These data suggest that the genetic ancestries identified in the pre-40ka individuals analysed so far went largely extinct or were assimilated by subsequent expansions1,9. 2c). Emergence of human-adapted Salmonella enterica is linked to the Neolithization process. Here we will provide you only interesting content, which you will like very much. 27, 576582 (2017). 40,000-year-old individual from Asia provides insight into early population structure in Eurasia. By co-analysing previously published data with our newly reported genomes associated with the Magdalenian from La Marche (18ka) and Pincevent (15ka) in western and northern France, respectively, and Maszycka (1816ka) in southern Poland, we confirm that the Goyet Q116-1 ancestry survived in all studied Magdalenian-associated genomes besides in Gravettian and Solutrean-associated individuals from southwestern and western Europe (Fig. The MDS analysis showing the genetic affinity among European hunter-gatherers was based on the distance matrix derived from outgroup f3-statistics, in the form 1f3(Mbuti.DG; pop1, pop2) and performed with classical MDS algorithm (cmdscale) implemented in R 3.5.1. This channel is about data science, learning, and productivity. 2010, pdb.prot5448 (2010). Google Scholar. Ancient genomes from present-day France unveil 7,000 years of its demographic history. Second, data-driven product development meshes very well with my own philosophy, commonly known as the 80/20 rule, where 80% of the results come from just about 20% of inputs. Max Planck Institute for Evolutionary Anthropology. 13, 24472461 (2018). is also supported by the Deutsche Forschungsgemeinschaft (DFG FOR 2237). All Rights Reserved. Therefore, the broader terms archaeological culture or simply culture are used here to refer to archaeologically defined material cultures without implying links to modern anthropological and/or ethnographical concepts of culture. Created by DataSciencePR. In this video, I had the opportunity to talk with Tina Huang, a Data Scientist at one of the FAANG companies. 255, 106796 (2021). Tina Huang is one of the top three students to show up to compete. Low latency, reasonably low communication overhead and ability to support real time applications are the reasons for . Los Angeles, California, United States. B 370, 20130624 (2015).